Marketing authorizations

 
Title Link
FDA - CDER - subscribe to mailing lists free of charge. http://www.fda.gov/cder/cdernew/listserv.html 
FDA -(proposed) Pediatric Rule - Regulations Requiring Manufacturers to Assess the Safety and Effectiveness of New Drugs and Biological Products in Pediatric Patients - 21 CFR Parts 201, 312, 314, and 601 - (99 pages) http://www.fda.gov/cder/guidance/pedrule.pdf 
US. District Court for the District of Columbia - Memorandum and opinion -October 25, 2001 - (24 pages) http://www.cei.org/pdfs/pediatric-ruling.pdf 
Kurt R. Karst - Comments Pediatric Testing of Prescription Drugs: the Food and Drug Administration's Carrot and Stick for the Pharmaceutical Industry - American University Law Review Vol. 49:739 - 2000 - (34 pages) http://www.wcl.american.edu/journal/lawrev/49/karst.pdf 
Swissmedic Journal 1/2002 (32 pages) http://www.swissmedic.ch/files/pdf/01_2002.pdf 
Swissmedic - home page (english) http://www.swissmedic.ch/?lang=2 
RxList - The Top 200 Prescriptions* for 2000 by Number of US Prescriptions Dispensed Generic name link leads to Drug Monograph information where available. http://www.rxlist.com/top200.htm 
Swissmedic - Commentaires concernant le formulaire «Demande d’autorisation / modification» http://www.swissmedic.ch/files/pdf/Commentaires%20sur%20le%20formulaire%20demande%20d%27autorisation%20-%20modification.pdf 
FDA - Guidelines for Drug Master Files - September 1989 http://www.fda.gov/cder/guidance/dmf.htm 
Federal Food, Drug and Cosmetic Act - Portions revised or new- As Amended by the FDA Modernization Act of 1997 http://www.fda.gov/opacom/laws/fdcact/fdctoc.htm 
EMEA - Fees payable to the EMEA - Human Medicinal Products http://www.emea.eu.int/htms/general/admin/fees/feesh.htm  http://www.emea.eu.int/pdfs/general/direct/fees/711499en.pdf 
EMEA - Market Authorisation Withdrawals (Also includes Suspensions of MA) http://www.emea.eu.int/htms/human/withdraw/withdraw.htm 
EMEA - CPMP Opinions on approval or refusal of marketing authorizations http://www.emea.eu.int/htms/human/opinion/opinion.htm 
EMEA - CPMP/EWP/240/95 Note for Guidance on Fixed Combination Medicinal Products (CPMP adopted April. 96) - (5 pages)  http://www.emea.eu.int/pdfs/human/ewp/024095en.pdf 
U.S. - EC MRA (Mutual Recognition Agreement) Pharmaceutical Good Manufacturing Practices Annex - Sectoral Annex for Pharmaceutical Good Manufacturing Practices GMPs) - (29 pages) http://pharmacos.eudra.org/F2/mra/doc/mraecus.pdf 
U.S. - EC MRA - Joint Procedure for the Information Exchange of Serious or Life-Threatening Human / Animal Pharmaceutical Product Quality Defects and Recalls - (7 pages) http://www.emea.eu.int/pdfs/technical/mra/usa/008600en.pdf 
Council Directive 93/42/EEC of 14 June 1993 concerning medical devices http://europa.eu.int/eur-lex/en/lif/dat/1993/en_393L0042.html 
Council Directive 90/385/EEC of 20 June 1990 on the approximation of the laws of the Member States relating to active implantable medical devices http://europa.eu.int/eur-lex/en/lif/dat/1990/en_390L0385.html 
Swissmedic - form - requête d'autorisation d'exploitation - (fabrication, importation, exportation, commerce, etc.) - (3 pages) http://www.swissmedic.ch/files/pdf/B3.3.12-f.pdf 
Swissmedic - form - requête d'autorisation d'exploitation - annexe A - Fabrication de médicaments (manufacture of drugs) - (4 pages) http://www.swissmedic.ch/files/pdf/B3.3.13-f.pdf 
Swissmedic - form - requête d'autorisation d'exploiter - annexe B - Importation de médicaments (prêts à l'emploi) (drug imports) - (2 pages) http://www.swissmedic.ch/files/pdf/B3.3.14-f.pdf 
Swissmedic - form - requête d'autorisation d'exploiter - annexe C - Commerce de gros de médicaments (drug wholesaler authorization) - (2 pages) http://www.swissmedic.ch/files/pdf/B3.3.15-f.pdf 
Swissmedic - form - requête d'autorisation d'exploiter - annexe D - Exportation de médicaments (prêts à l'emploi) (ready-made drug exports) - (2 pages) http://www.swissmedic.ch/files/pdf/B3.3.16-f.pdf 
Swissmedic - form - requête d'autorisation d'exploiter - annexe E - Commerce à l'étranger de médicaments (sale of drugs in foreign countries) - (2 pages) http://www.swissmedic.ch/files/pdf/B3.3.17-f.pdf 
Swissmedic - form - requête d'autorisation d'exploiter - annexe F - Prélèvement de sang pour la transfusion ou la fabrication de médicaments (blood taking for transfusion / drug manufacturing) - (2 pages) http://www.swissmedic.ch/files/pdf/B3.3.17-f.pdf 
Swissmedic - form - demande d'autorisation / modification - (4 pages) http://www.swissmedic.ch/files/pdf/B3.1.11-f.pdf 
Swissmedic - form - announce d'effets indésirables suspectés d'un médicament (EI) (possible drug adverse event) - (2 pages) http://www.swissmedic.ch/files/pdf/B3.2.16_Formulaire_d%27annoce_EI.pdf 
Swissmedic - form - demande d'octroi d'une autorisation Swissmedic pour médicament à l'expiration de l'enregistrement OICM - (change from IOCM to Swissmedic authorization) (4 pages) http://www.swissmedic.ch/files/pdf/B3.1.96_demande_d%27octroi_%E0_l%27%E9ch%E9ance_d%27enregistrement_OICM-usage_humain.dot 
Swissmedic - form - statut des demandes d'autorisation déposées à l'étranger http://www.swissmedic.ch/files/pdf/B3.1.92%20demandes%20d%27autorisation%20d%E9pos%E9e%20%E0%20l%27%E9tranger.doc 
Swissmedic - form - produit d'origine animale présentant un risque d'EST - (4 pages) http://www.swissmedic.ch/files/pdf/B3.1.91-f.pdf 
Swissmedic - form - renseignements concernant les fabricants - (6 pages) http://www.swissmedic.ch/files/pdf/B3.1.28-f.pdf 
Swissmedic - list of countries from which imports of drugs in Switzerland are possible (following a simplified procedure) http://www.swissmedic.ch/overall.asp?theme=0.00107&theme_id=362&nm4prm=cGFnZT0xJmlkPTE5NjM= 
ICH - Technical Requirements for Registration of Pharmaceuticals for Human Use - ICH M2 EWG Electronic Common Technical Document Specification - 2002 - (160 pages) http://www.fda.gov/cder/m2/eCTD%20Step%202/eCTD%20Specification%20v2-0-1.pdf 
FDA - Electronic Common Technical Document FDA Regional Information - (14 pages) http://www.fda.gov/cder/regulatory/ersr/FDARegional/FDA_regional_eCTD/FDA%20Regional%20-%20Instructions.doc 
AAC Consulting Group - Audit of Schering-Plough Manufacturing Facility - 2000, (15 pages) http://www.citizen.org/documents/schering200.pdf 
Food and Drug Law, Regulation, and Education Global Trends - Issue 2 • April 2000 - (48 pages) http://www.fdli.org/pubs/Update/2000/issue2.pdf 
NCAHF (National Council Against Health Fraud ) - Analysis of the Reports of the White House Commission on Complementary and Alternative Medicine Policy (WHCCAMP) http://www.ncahf.org/whc/00.html 
White House Commission on Complementary and Alternative Medicine Policy - Final Report -March 2002 http://www.whccamp.hhs.gov/finalreport.html 
Public Citizen - Backgrounder Unprecedented Number of Drug Withdrawals Point to Problems in FDA Drug Approval Process http://www.citizen.org/congress/regulations/issue_areas/drug_devise/articles.cfm?ID=7442 
FY 2001 Performance Report to Congress for the Prescription Drug User Fee Act of 1992 as reauthorized and amended by the Food and Drug Administration Modernization Act of 1997 http://www.fda.gov/oc/pdufa/report2001/pdufareport.html 
Holly Aprea - FDA Regulation of Tobacco A Closer Look at the Forces Contributing to the Movement for Regulation - 2001 - (118 pages) http://www.american.edu/academic.depts/honors/CurrentStudents/capstones/aprea.pdf  
Chrisanthi Avgerou, Tony Cornford and Elias Mossialos - Drug Use Information Systems: A European Perspective, August 1995.- (26 pages) http://www.lse.ac.uk/Depts/lsehsc/papers/Discussion_Papers/dp2.pdf 
U.S. Supreme Court decision - FDA v. Brown & Williamson Tobacco Corp. (98-1152) 153 F.3d 155, affirmed. (39 pages & 32 pages) - tobacco as a drug/device http://supct.law.cornell.edu/supct/pdf/98-1152P.ZO  http://supct.law.cornell.edu/supct/pdf/98-1152P.ZD  
Pharmaceuticals in the European Union - booklet - (31 pages) http://pharmacos.eudra.org/F2/pharmacos/docs/brochure/brochurenov99.pdf 
FDA Backgrounder - FDA's Budget Request for FY 2002 http://www.fda.gov/opacom/backgrounders/budget.html 
FDA - Milestones in U.S. Food and Drug Law History http://www.fda.gov/opacom/backgrounders/miles.html 
FDA- FY 2002 Congressional Budget Request - Various documents http://www.fda.gov/oc/oms/ofm/budget/2002/2002budget.htm 
JAAC 59.34 -Décision de la Commission fédérale de recours en matière de douanes du 27 octobre 1994 - Capsules Y http://www.vpb.admin.ch/franz/doc/59/59.34.html 
FDA - CDER Manual of Policies and Procedures MaPPs http://www.fda.gov/cder/mapp.htm 
Procedure on the granting of marketing authorisations by central and Eastern European Countries for medicinal products for human use - December 1999 - (18 pages) http://www.il.waw.pl/centralised_procedure.pdf 
Note for Guidance on Specifications: test procedures and acceptance criteria for biotechnological/biological products - (17 pages) http://www.emea.eu.int/pdfs/human/ich/036596en.pdf 
Note for Guidance on Specifications: test procedures and acceptance criteria for herbal drugs, herbal drug preparations and herbal medicinal products - (19 pages) http://www.emea.eu.int/pdfs/human/qwp/282000en.pdf 
FDA - Notice - Establishment of Prescription Drug User Fee Rates for Fiscal Year 2000and 2002 http://www.fda.gov/cber/genadmin/fr-estab.pdf http://www.pharmcast.com/FederalRegistrar/Yr2002/011402/UserFee011602.htm 
21 CFR (Code of Federal Regulations) Parts 210 and 211 Part 210 - Current Good Manufacturing Practice http://www.fda.gov/cder/dmpq/cgmpregs.htm 
FDA - Main page on Good Manufacturing Practices http://www.fda.gov/cder/dmpq/index.htm 
FDA - Compliance Program Guidance Manual for FDA Staff: Drug Manufacturing Inspections http://www.fda.gov/cder/dmpq/compliance_guide.htm 
Report of the Committee on the Drug Review Process of the Science Advisory Board to Health Canada - (17 pages) http://www.hc-sc.gc.ca/hpb/science/pdf/drg/drug_e.pdf 
EMA - Annual Report 2001 - (72 pages) http://www.emea.eu.int/pdfs/general/direct/emeaar/005201en.pdf 
Global Market Liberalization, Mutual Recognition Agreements, and Industry Standards: International Competition, Regulatory Cooperation, and Consumer Protection in North America and Europe -(165 pages) http://transatlantic.gwu.edu/~tranconf/publication.pdf 
Joshua T. Cohen Keith Duggar George M. Gray Silvia Kreindel - Evaluation of the Potential for Bovine Spongiform Encephalopathy in the United States - Harvard Center for Risk Analysis Harvard School of Public Health - (127 pages) http://www.aphis.usda.gov/oa/bse/mainreporttext.pdf http://www.fda.gov/oc/bse/harvard_study.html 
FDA - A Trial of St. John's Wort (Hypericum perforatum) for the Treatment of Major Depression http://nccam.nih.gov/ne/press-releases/stjohnswort/q-and-a.htm  
FDA - Medication Guide Accutane Capsules (isotretinoin) http://www.fda.gov/cder/drug/infopage/accutane/medicationguide.htm#important warnings 
A National Survey of Oncologists Regarding The Food and Drug Administration Conducted by the polling company for the Competitive Enterprise Institute (CEI) - (12 pages) http://www.cei.org/pdf/2987.pdf 
Barsky AJ, Saintfort R, Rogers MP, Borus JF. Nonspecific medication side effects and the nocebo phenomenon. JAMA. 2002;287:622-627 - (6 pages) http://jama.ama-assn.org/issues/v287n5/rpdf/jsc10377.pdf 
Center for Drug Evaluation and Research - 2001 Report to the Nation - Improving Public Health Through Human Drugs - (50 pages) http://www.fda.gov/cder/reports/rtn/2001/rtn2001.pdf 
FDA - 2002 Workshop on Pharmacogenetics / Pharmacogenomics in Drug Development and Regulatory Decision-Making - May 16-17th, 2002 - (65 pages) http://www.fda.gov/cder/calendar/meeting/phrma52002/workbook.pdf 
Investigators' Reports Maker of Growth Hormone Feels Long Arm of Law - FDA Consumer magazine September-October 1999 http://www.fda.gov/fdac/departs/1999/599_irs.html 
FDA - Rule - New Drug and Biological Drug Products; Evidence Needed to Demonstrate Effectiveness of New Drugs When Human Efficacy Studies Are Not Ethical or Feasible http://www.fda.gov/OHRMS/DOCKETS/98fr/98n-0237-nfr0001-vol1.pdf 
JAAC 66.16 Décision de la Commission fédérale de recours en matière d'alcool - August 20, 2001 http://www.vpb.admin.ch/franz/contenu_fr.html 
Proposal for a Regulation and Directive - laying down Community procedures for the authorisation and supervision of medicinal products for human use - November 2001 - (200 pages) http://pharmacos.eudra.org/F2/review/doc/finaltext/011126-COM_2001_404-EN.pdf 
ICH M2 EWG Electronic Common Technical Document Specification- Technical Requirements for registration of pharmaceuticals for human use - February 12, 2002 - (160 pages) http://www.fda.gov/cder/guidance/5017dft.pdf 
ICH Q1E - Draft Consensus Guideline Evaluation of Stability Data - 7 February 2002 http://www.fda.gov/cder/guidance/4983dft.pdf 
ICH Q1F Draft Consensus Guideline - Stability Data Package for Registration in Climatic Zones III and IV - February 7, 2002 - (5 pages) http://www.fda.gov/cder/guidance/4984dft.pdf 
Swissmedic - Guide to the regulation of medical devices http://www.swissmedic.ch/md/files/leitf-e.html 
OTA - Drug Labeling in Developing Countries - 1993 http://www.wws.princeton.edu/cgi-bin/byteserv.prl/~ota/disk1/1993/9321/9321.PDF 
The National Organization for the Reform of Marijuana Laws - home page http://www.norml.org/ 
Rapport sur le Cannabis de la Commission fédérale pour les questions liées aux drogues - CFLD - Septembre 1999 - (114 pages) http://www.bag.admin.ch/sucht/publikationen/f/cannabis.pdf 
FDA - Guidance for Industry Providing Regulatory Submissions in Electronic Format — ANDAs - (10 pages) http://www.fda.gov/cder/guidance/5004fnl.pdf 
Ordonnance de l'OFSP du 8 novembre 1996 sur les précurseurs et autres produits chimiques utilisés pour la fabrication de stupéfiants et de substances psychotropes (Ordonnance de l'OFSP sur les précurseurs, O Prec-OFSP) http://www.admin.ch/ch/f/rs/8/812.121.31.fr.pdf 
Ordonnance du 8 mars 1999 sur la prescription médicale d'héroïn http://www.admin.ch/ch/f/rs/8/812.121.6.fr.pdf 
Loi fédérale du 21 mars 1969 sur le commerce des toxiques (Loi sur les toxiques http://www.admin.ch/ch/f/rs/8/813.0.fr.pdf 
Ordonnance du 19 septembre 1983 sur les toxiques (Otox) http://www.admin.ch/ch/f/rs/8/813.01.fr.pdf 
Ordonnance du 25 août 1999 sur l'utilisation d'organismes dans l'environnement (Ordonnance sur la dissémination dans l'environnement, ODE) http://www.admin.ch/ch/f/rs/8/814.911.fr.pdf 
Ordonnance du 25 août 1999 sur l'utilisation des organismes en milieu confiné (Ordonnance sur l'utilisation confinée, OUC) http://www.admin.ch/ch/f/rs/8/814.912.fr.pdf 
Loi fédérale du 9 octobre 1992 sur les denrées alimentaires et les objets usuels (loi sur les denrées alimentaires, LDAI); RS 817.0 http://www.admin.ch/ch/f/rs/8/817.0.fr.pdf 
Ordonnance du 1 er mars 1995 sur les denrées alimentaires (ODAI); RS 817.02 http://www.admin.ch/ch/f/rs/8/817.02.fr.pdf 
Ordonnance du 26 juin 1995 sur les additifs admis dans les denrées alimentaires (O sur les additifs, OAdd); RS 817.021.22 http://www.admin.ch/ch/f/rs/8/817.021.22.fr.pdf 
Ordonnance du 26 juin 1995 sur les substances étrangères et les composants dans les denrées alimentaires (O sur les substances étrangères et les composants, OSEC); RS 817.021.23 http://www.admin.ch/ch/f/rs/8/817.021.23.fr.pdf 
Ordonnance du 19 novembre 1996 concernant la procédure d'autorisation relative aux denrées alimentaires OGM, aux additifs OGM et aux auxiliaires technologiques OGM (OAOGM); RS 817.021.35 http://www.admin.ch/ch/f/rs/8/817.021.35.fr.pdf 
Ordonnance du 6 mars 2000 sur l'indication du pays de production des denrées alimentaires, des additifs alimentaires et des matières premières (Ordonnance sur l’indication de la provenance des matières de base, OIPMB); RS 817.021.51. http://www.admin.ch/ch/f/rs/8/817.021.51.fr.pdf 
Ordonnance du 26 juin 1995 sur la valeur nutritive (ONutr); RS 817.021.55. http://www.admin.ch/ch/f/rs/8/817.021.55.fr.pdf 
Ordonnance du 1er mars 1995 sur les objets usuels (OUs); RS 817.04 http://www.admin.ch/ch/f/rs/8/817.04.fr.pdf 
Ordonnance du 26 juin 1995 sur les cosmétiques (OCos); RS 817.042.1 http://www.admin.ch/ch/f/rs/8/817.042.1.fr.pdf 
Convention intercantonale du 3 juin 1971 sur le contrôle des médicaments http://www.admin.ch/ch/f/rs/c812_101.html 
Ordonnance du 23 août 1989 concernant les produits immunobiologique http://www.admin.ch/ch/f/rs/8/812.111.fr.pdf 
Loi fédérale du 3 octobre 1951 sur les stupéfiants et les substances psychotropes (Loi sur les stupéfiants, LStup http://www.admin.ch/ch/f/rs/8/812.121.fr.pdf 
Ordonnance du 29 mai 1996 sur les stupéfiants et les substances psychotropes (Ordonnance sur les stupéfiants, Ostup) http://www.admin.ch/ch/f/rs/8/812.121.1.fr.pdf 
Ordonnance de l'OFSP du 12 décembre 1996 sur les stupéfiants et les substances psychotropes (Ordonnance de l'OFSP sur les stupéfiants, Ostup-OFSP) http://www.admin.ch/ch/f/rs/8/812.121.2.fr.pdf 
Ordonnance du 29 mai 1996 sur les précurseurs et autres produits chimiques utilisés pour la fabrication de stupéfiants et de substances psychotropes (Ordonnance sur les précurseurs, OPrec) http://www.admin.ch/ch/f/rs/8/812.121.3.fr.pdf 
Ordonnance du 1er mars 1995 sur le tabac et les produits du tabac (O sur le tabac, OTab); RS 817.06 http://www.admin.ch/ch/f/rs/8/817.06.fr.pdf 
Loi fédérale du 18 décembre 1970 sur la lutte contre les maladies transmissibles de l'homme (Loi sur les épidémies); RS 818.101 http://www.admin.ch/ch/f/rs/8/818.101.fr.pdf 
Arrêté fédéral du 22 mars 1996 sur le contrôle du sang, des produits sanguins et des transplants; RS http://www.admin.ch/ch/f/rs/8/818.111.fr.pdf 
ATF 127 IV 178 - Decision of the Swiss Federal Tribunal - regarding hallucinogen mushrooms - July 4, 2001 - http://www.eurospider.ch/buge3/index/127_IV.html 
U.S. Federal Drug and Food Administration - FDA - home page http://www.fda.gov/guidance 
Ordonnance du 26 juin 1996 sur le contrôle du sang, des produits sanguins et des transplants (Ordonnance sur le contrôle du sang); RS 818.111.3 http://www.admin.ch/ch/f/rs/8/818.111.3.fr.pdf 
Ordonnance du 26 juin 1996 sur les essais cliniques de produits immunologiques; RS: 818.124. http://www.admin.ch/ch/f/rs/8/818.124.1.fr.pdf 
Ordonnance du 13 janvier 1999 sur la déclaration des maladies transmissibles de l'homme (Ordonnance sur la déclaration); RS 818.141.1 http://www.admin.ch/ch/f/rs/8/818.141.1.fr.pdf 
Ordonnance du 24 janvier 1996 sur les dispositifs médicaux (ODim); RS 819.124 http://www.admin.ch/ch/f/rs/8/819.124.fr.pdf 
Convention du 8 octobre 1970 pour la reconnaissance mutuelle des inspections concernant la fabrication des produits pharmaceutiques (avec notes explicatives); RS 0.812.101 http://www.admin.ch/ch/f/rs/i8/0.812.101.fr.pdf 
Stability Testing of New Drug Substances and Products (Step 5) http://www.ifpma.org/pdfifpma/q1arstep4.pdf 
Guideline on Photostability Testing (Step 5) http://www.ifpma.org/pdfifpma/q1b.pdf 
Guideline on Stability Testing for New Dosage Forms Step 5 http://www.ifpma.org/pdfifpma/q1c.pdf 
Guideline on Impurities in New Drug Substances (Revised Guideline) (Step 3) http://www.ifpma.org/word/Q3Arstep2.doc 
Impurities in New Drug Products (Revised Guideline) (Step 3) http://www.ifpma.org/word/Q3Brstep2.doc 
Q6B Guideline on Biotechnological Substances (Step 5) http://www.ifpma.org/pdfifpma/Q6bstep4.pdf 
Q7A Guideline on Good Manufacturing Practices for Active Pharmaceutical Ingredients Step 5 http://www.ifpma.org/pdfifpma/Q7Astep4.PDF 
Web site of the European Agency for the Evaluation of Medicinal Products (EMEA) http://www.emea.eu.int/# 
EMEA Web Site for Human Medicines http://www.emea.eu.int/index/indexh1.htm 
EMEA General Information for Sponsors of Orphan Medicinal Products (EMEA/4795/00) http://www.emea.eu.int/pdfs/human/comp/479500en.p 
European Commission Enterprise DG http://pharmacos.eudra.org 
European Commission, Enterprise Directorate-General, G10 Medicines High Level Group on Innovation and Provision of Medicines, Single market, implementation and legislation for consumer goods, Consultation Paper, p 20 http://pharmacos.eudra.org/F3/g10/docs/g10an1.pdf 
Information on the high level group on Innovation and the Provision of Medicines http://pharmacos.eudra.org/F3/g10/p2.htm 
Report from the Commission on the experience acquired as a result of the operation of the procedures for granting marketing
authorisations for medicinal products laid down in Regulation (EEC) N° 2309/93, 2001, (p 33)
http://pharmacos.eudra.org/F2/review/doc/reviewrapport/rap_fv_en.pdf 
European Commission, Enterprise Directorate-General, Pharmaceutical Legislation Review 2001, Single market : management & legislation for consumer goods Pharmaceuticals : regulatory framework and market authorisations, (p 77) http://pharmacos.eudra.org/F2/review/doc/2codehumain_fr_18-7-2001.pdf 
Reform of EU Pharmaceutical Legislation, Brussels, 18 July 2001, MEMO/01/267 http://pharmacos.eudra.org/F2/review/doc/brief_m01_267_en.pdf 
List of directives and regulations of the European Union regarding proprietary medicinal products http://europa.eu.int/eur-lex/en/lif/reg/en_register_1530.html 
Council Directive 65/65/EEC of 26 January 1965 on the approximation of provisions laid down by Law, Regulation or Administrative Action relating to proprietary medicinal products http://europa.eu.int/eur-lex/en/lif/dat/1965/en_3 
Council Directive 75/318/EEC of 20 May 1975 on the approximation of the laws of Member States relating to analytical, pharmaco-toxicological and clinical standards and protocols in respect of the testing of proprietary medicinal products http://europa.eu.int/eur-lex/en/lif/dat/1975/en_3 
Second Council Directive 75/319/EEC of 20 May 1975 on the approximation of provisions laid down by Law, Regulation or Administrative Action relating to proprietary medicinal products http://europa.eu.int/eur-lex/en/lif/dat/1975/en_3 
Council Directive 78/25/EEC of 12 December 1977 on the approximation of the laws of the Member States relating to the colouring matters which may be added to medicinal products http://europa.eu.int/eur-lex/en/lif/dat/1978/en_3 
Council Directive 89/342/EEC of 3 May 1989 extending the scope of Directives 65/65/EEC and 75/319/EEC and laying down additional provisions for immunological medicinal products consisting of vaccines, toxins or serums and allergens http://europa.eu.int/eur-lex/en/lif/dat/1989/en_3 
Commission Regulation (EC) No 2141/96 of 7 November 1996 concerning the examination of an application for the transfer of a marketing authorization for a medicinal product falling within the scope of Council Regulation (EC) No 2309/93 http://europa.eu.int/eur-lex/en/lif/dat/1996/en_3 
Home Page of the Center for Drug Evaluation and Research (FDA) - home page http://www.fda.gov/cder/ 
List of Guidance Documents of CDER http://www.fda.gov/cder/guidance/index.htm 
Center for Drug Evaluation and Research, 2000 Report to the Nation Improving Public Health Through Human Drugs - (46 pages) http://www.fda.gov/cder/reports/RTN2000/RTN2000.PDF 
Center for Drug Evaluation and Research, CDER 1999 Report to the Nation Improving Public Health Through Human Drugs http://www.fda.gov/cder/reports/rtn99.pdf 
CDER, 1997 Report to the Nation: Improving Public Health Through Human Drugs http://www.fda.gov/cder/reports/rptntn97.pdf  
FDA Center for Food Safety and Applied Nutrition, Cosmetic Handbook http://www.cfsan.fda.gov/~dms/cos-hdbk.html 
Home Page of the FDA Center for Food Safety & Applied Nutrition http://www.cfsan.fda.gov 
Home Page of the FDA Center for Food Safety & Applied Nutrition regarding cosmetics http://vm.cfsan.fda.gov/~dms/cos-toc.html 
Swiss Federal Office for Public Health, Annual Report 2000 on biologic products http://www.bag.admin.ch/heilmitt/biologik/jahrb00 
Swiss Federal Law on Therapeutic Products (English Translation); RS http://www.bag.admin.ch/heilmitt/gesetz/HMG_Engl.pdf 
Swiss Department of Home Affairs, Rapport de consultation concernant les ordonnances sur les produits thérapeutiques Berne, 17 octobre 2001 http://www.bag.admin.ch/heilmitt/aktuell/f/vern_ber.pdf 
Canton of Geneva, Dons d'organes - loi genevoise: du consentement explicite au consentement présumé http://www.geneve.ch/social/donsorg/welcome.html 
E-Letter on Drugs for Severe Psychiatric Illnesses, Public Citizen http://www.citizen.org/eletter/# 
Form for the registration of manufacturers and devices In Vitro Diagnostic Medical Devices Directive, Article 10 http://www.bag.admin.ch/md/pdf/ivdform-fe.pdf 
Form for the registration of information relating to certification of In Vitro Diagnostic Medical Devices (Annexes III to VII) - In Vitro Diagnostic Medical Devices Directive http://www.bag.admin.ch/md/pdf/ivdzert-fe.pdf 
Normes techniques pour les dispositifs médicaux - Ordonnance sur les dispositifs médicaux (ODim) http://www.bag.admin.ch/md/pdf/normenf.pdf 
Liste des numéros d’identification des organes responsables de l’évaluation de la conformité des dispositifs médicaux reconnus en Suisse (articles 8 et 11 ODim) July 3, 2001 http://www.bag.admin.ch/md/pdf/kbs-f.pdf  
Notification according to art. 6 MDO - one notification for each device or group of devices. http://www.bag.admin.ch/md/pdf/me-formdfie.pdf 
Dispositifs médicaux: annonce des incidents par les utilisateurs http://www.bag.admin.ch/md/pdf/vi_factf.pdf 
Eric M. Blumberg, Abbott Laboratories Consent Decree and Individual Responsibility Under the Federal Food, Drug, and Cosmetic Act, 55 Food and Drug Law Journal 145-150 (2000) - (6 pages) http://www.fdli.org/pubs/Journal%20Online/55_1/art9.pdf 
Accord entre la Communauté européenne et la Confédération suisse relatif à la reconnaissance mutuelle en matière d’évaluation de la conformité - FF 1999 5847 - (80 pages) http://www.europa.admin.ch/ba/off/abkommen/f/abf_tbt.pdf 
Rapport du Conseil fédéral sur l’inventaire et l’évaluation des procédures de droit fédéral de l’économie (Réponse au Postulat David 96.3607 «Charges administratives») - February 17, 1999 - (181 pages, at 84, 101, 113, 172) http://www.admin.ch/ch/f/ff/1999/7603.pdf 
Federal Council, Message concernant la loi fédérale sur la protection contre les substances et les préparations dangereuses (Loi sur les produits chimiques, LChim) du 24 novembre 1999 - FF 2000 623 - (161 pages) http://www.admin.ch/ch/f/ff/2000/623.pdf 
Draft - Loi fédérale sur la protection contre les substances et les préparations dangereuses (Loi sur les produits chimiques, LChim) - FF 200 784 - (22 pages) http://www.admin.ch/ch/f/ff/2000/784.pdf 
Decision of the Swiss Federal Tribunal of November 1, 2001 - 2P.67/2001 http://wwwsrv.bger.ch/cgi-bin/AZA/MapProcessorCGI_AZA?mapfile=pull/ConvertDocFrameCGI.map&ri=fr&lang=fr&ds=AZA_pull&d=01.11.2001_2P.67%2f2001&pa=2%7emelatonine%4010%7emelatonine%404%7e& 
Decision of the Swiss Federal Tribunal of June 14, 2001, 6S.15/2001/vlc regarding marijuane and hachisch http://wwwsrv.bger.ch/cgi-bin/AZA/MapProcessorCGI_AZA?mapfile=pull/ConvertDocFrameCGI.map&ri=fr&lang=fr&ds=AZA_pull&d=14.06.2001_6S.15%2f2001&pa=2%7eoicm%4010%7eoicm%404%7e&  
Decision of the Swiss Federal Tribunal - ATF 81 I 351 -October 26, 1955 - regarding fees for obtaining marketing authorizations http://www.eurospider.ch/buge3/index/81_I.html 
Medical Devices Ordinance (MDO) Information on Article 13 Reporting of serious incidents http://www.bag.admin.ch/md/pdf/VI-Indus-InfoE.pdf 
European Committee for Standardization - CEN - home page http://www.cenorm.be/  
List of medicines subject to prescription, 2000 edition http://www.coe.fr/soc-sp/sante/Alpha%20List%202000%20E.zip 
Council of Europe - Committee of Ministers - Resolution AP(2000) on the classification of medicines which are obtainable only on medical prescription - March 15, 2000 http://cm.coe.int/ta/res/resAP/2000/2000xp1.htm 
Council of Europe - Committee of Ministers . Resolution AP (99) 2- on warning phrases for certain categories of medicines http://www.coe.fr/cm/ta/res/resAP/1999/99xp2.htm 
Council of Europe - Committee of Ministers - Resolution AP (96) - on the declaration of excipients present in pharmaceutical products - October 2, 1996 http://cm.coe.int/ta/res/1996/96xp1.html 
Public Health Committee - Committe of experts on pharmaceutical questions - Note from the Austrian Delegation on the requirements applying to prescriptions - Medicines for human use except narcotics http://www.coe.fr/soc-sp/sante/97spt19reve.zip 
Public Health Committee - Committee of experts on pharmaceutical questions - Final Report on the importation of unregistered medicines - Multicountry comparisons - April 2000 http://www.coe.fr/soc-sp/sante/SPT28E%20-%20médicaments%20non%20enregistrés%20-%20Autriche.zip 
FDA, Devices classification - previous correspondance http://www.fda.gov/cdrh/devadvice/21.html#contents 
FDA - Product Code Classification Database http://www.fda.gov/cdrh/prodcode.html 
FDA - Good Manufacturing Practices (GMP) / Quality System (QS) Regulation http://www.fda.gov/cdrh/devadvice/32.html#contents 
FDA - CDRH Annual Report Fiscal Year 2000 http://www.fda.gov/cdrh/annual/fy2000/annualreport-2000.pdf 
FDA - Bovine Spongiform Encephalopathy (BSE) http://www.fda.gov/cber/bse/bse.htm 
FDA - CBER Guidances / Guidelines / Points to Consider  http://www.fda.gov/cber/guidelines.htm 
FDA - CBER - Tissue Related Documents http://www.fda.gov/cber/tissue/docs.htm 
John Kamp, Daniele Troy, Elizabeth Alexander - FDA Marketing v. First Amendment: Washington Legal Foundation Legal Challenges to Off-Label Policies May Force Unprecedented Changes at FDA - 54 Food and Drug Law Journal - (12 pages) http://www.fdli.org/pubs/Journal%20Online/54_4/art4.pdf 
ATF 99 Ia 370 - decision of the Swiss Federal Tribunal regarding sale by Migro of Vitamins C http://www.eurospider.ch/buge3/index/99_I.html 
ATF 127 II 91 - decision of the Swiss Federal Tribunal regarding an advertisement for milk as preventing osteoporose http://www.eurospider.ch/buge3/index/127_II.html 
PERF - Pan European Regulatory Forum - home page - "The ultimate aim of this programme is the transposition of all technical regulations and European technical acts into the national legislation of central and eastern European countries (CEECs)" http://perf.eudra.org/ 
European Commission - Pharmaceuticals in the European Union - Information brochure - (42 pages) http://pharmacos.eudra.org/F2/pharmacos/docs/brochure/pharmaeu.pdf 
COMMISSION REGULATION (EC) No 847/2000 of 27 April 2000 laying down the provisions for implementation of the criteria for designation of a medicinal product as an orphan medicinal product and definitions of the concepts http://pharmacos.eudra.org/F2/orphanmp/doc/rev1/en1.pdf 
Notice to Applicants - Volume 2B - Medicinal products for human use - Presentation and content of the dossier - 1998 - (206 pages) http://pharmacos.eudra.org/F2/eudralex/download/volpdf/vol2/vol2ben.pdf 
Guidelines - Volume 3A - Medicinal products for human use - Quality and biotechnology - 1998 - (417 pages) http://pharmacos.eudra.org/F2/eudralex/download/volpdf/vol3/vol3aen.pdf 
Guidelines - Volume 3B - Medicinal products for human use - Safety, environment and information - 1998 - (240 pages) http://pharmacos.eudra.org/F2/eudralex/download/volpdf/vol3/Vol3ben.pdf 
Guidelines - Volume 3C - Medicinal products for human use - Efficacy - 1998 - (402 pages) http://pharmacos.eudra.org/F2/eudralex/download/volpdf/vol3/Vol3cen.pdf 
Volume 4 - Good manufacturing practices - Medicinal products for human and veterinary use - (153 pages)  http://pharmacos.eudra.org/F2/eudralex/download/volpdf/vol4/vol4en.pdf 
European Commission - Revision of Annex 14 to the EU Guide to Good Manufacturing Practice - Manufacture of medicinal products1 derived from human blood or human plasma - (7 pages)  http://pharmacos.eudra.org/F2/eudralex/vol-4/pdfs-en/gmpan14_en.pdf 
John Y. Chai, Medical Device Regulation in the United States and the European Union: A Comparative Study, 55 Food and Drug Law Journal 57-80 (2000), http://www.fdli.org/pubs/Journal%20Online/55_1/art4.pdf 
GAO - Dietary Supplements: Uncertainties in Analyses Underlying FDA's Proposed Rule on Ephedrine Alkaloids, July 1999, http://www.gao.gov/archive/1999/h299090.pdf 
GAO - Drug Safety: Most Drugs Withdrawn in Recent Years Had Greater Health Risks for Women, January 2001 http://www.gao.gov/new.items/d01286r.pdf 
GAO - Mutual Recognition Agreement: Update on the Food and Drug Administration's Progress in Assessing Equivalency of European Union Pharmaceutical Good Manufacturing Practice Regulatory Systems, August 1999 http://161.203.16.4/paprpdf2/162604.pdf 
GAO - Mutual Recognition Agreement: Food and Drug Administration's Progress in Assessing Equivalency of European Union Pharmaceutical Inspection Programs, February 1999 http://161.203.16.4/paprpdf2/161744.pdf 
GAO - Prescription Drugs, Many Factors Affected FDA's Approval of Selected 'Pipeline' Drugs, August 2000, http://www.gao.gov/archive/2000/he00140.pdf 
Judgment of the Court (Fifth Chamber) of 30 November 1983 - against Leendert van Bennekom - Case 227/82 - Concept of "Medicinal products" http://curia.eu.int/common/recdoc/indexaz/en/c1.htm 
Judgment of the Court of 28 February 1984 - Commission of the European Communities v Federal Republic of Germany - http://curia.eu.int/common/recdoc/indexaz/en/c1.htm#266/87 
Judgment of the Court (Fifth Chamber) of 27 May 1986. Société coopérative - Cophalux v Minister for Health - Rules governing the importation and marketing of medicinal products - Joined cases 87 and 88/85 http://curia.eu.int/common/recdoc/indexaz/en/c1.htm#266/87 
Judgment of March 21, 1991 - against Monteil and Samanni - Case 60/89 http://curia.eu.int/common/recdoc/indexaz/en/c2.htm 
Judgment of 16/04/1991, Upjohn / Farzoo - Case 112/89 http://curia.eu.int/common/recdoc/indexaz/en/c2.htm  
Judgment of May 20, 1992 - Commission / Germany - Case 290/90 http://curia.eu.int/common/recdoc/indexaz/en/c2.htm 
Judgment of December 12, 1993 - Pierrel and others / Ministero della Sanità - Case 83/92 http://curia.eu.int/common/recdoc/indexaz/en/c2.htm 
Judgment of October 5, 1995 - The Queen / Licensing Authority of the Department of Health and Norgine, ex parte Scotia Pharmaceuticals - Case C-440/93 http://curia.eu.int/common/recdoc/indexaz/en/c2.htm 
Judgment of the Court (Fifth Chamber) of 3 December 1998 - The Queen v The Licensing Authority established by the Medicines Act 1968 - Case C-368/96 - Marketing authorisation - Abridged procedure - Essentially similar products. http://curia.eu.int/common/recdoc/indexaz/en/c2.htm 
Judgment of the Court (Fifth Chamber) of 1 July 1993 - Eurim-Pharm GmbH v Bundesgesundheitsamt. - Case C-207/91.
- Parallel imports of pharmaceutical products
http://curia.eu.int/common/recdoc/indexaz/en/c2.htm 
Judgment of the Court of 12 November 1996 - The Queen v The Medicines Control Agency - Case C-201/94 - Parallel imports - Direct effect of Directive 65/65/EEC - Marketing authorization. http://curia.eu.int/common/recdoc/indexaz/en/c2.htm 
Judgment of the Court (Fifth Chamber) of 10 November 1994 - Lucien Ortscheit GmbH v Eurim-Pharm Arzneimittel GmbH.-Case C-320/93.
- Importation of medicines not agreed by the importing State - Prohibition of advertising
http://curia.eu.int/common/recdoc/indexaz/en/c2.htm 
Judgment of the Court of 8 June 1993 - Commission of the European Communities v Kingdom of Belgium - Case C-373/92 - Obligation to carry out examinations which have already been performed in the Member State of origin. http://curia.eu.int/common/recdoc/indexaz/en/c2.htm 
Judgment of the Court (First Chamber) of 15 May 1997 - Bioforce GmbH v Oberfinanzdirektion München - Case C-405/95 - Common customs tariff - Heading 3004 - Echinacea - Medicament. http://curia.eu.int/common/recdoc/indexaz/en/c2.htm 
European Union information on the safety of blood http://europa.eu.int/comm/health/ph/others/safety_blood/index_en.htm 
WHO - Herbal medicines - Assessment of safety and efficacy http://www.who.int/medicines/library/trm/medicinalplants/assessdocs.shtml 
WHO - Acupuncture http://www.who.int/medicines/library/trm/acupuncture/acupdocs.shtml 
WHO - Model Certificate of a Pharmaceutical Product http://www.who.int/medicines/organization/qsm/activities/drugregul/certification/modcert.html 
WHO - Guidelines on the implementation of the WHO certification scheme on the quality of pharmaceutical products moving in international commerce http://www.who.int/medicines/organization/qsm/activities/drugregul/certification/certifguide.html 
WHO - Achieving balance in national opioids control policy -- Guidelines for assessment - 2000 - (45 pages) http://www.who.int/medicines/library/qsm/who-edm-qsm-2000-4/Balance%20in%20Nat%20Opioids%20Control%20Policy%20final.pdf 
WHO - Good Manufacturing Practices http://www.who.int/medicines/organization/qsm/activities/qualityassurance/gmp/gmpcover.html 
International Conference on Harmonisation - ICH - home page http://www.ifpma.org/ich1.html 
ICH - Harmonisation process http://www.ifpma.org/ich4.html 
ICH - list of guidelines http://www.ifpma.org/ich5.html 
Convention relative à l’élaboration d’une Pharmacopée Européenne - conclue à Strasbourg le 22 juillet 1964 - entrée en vigueur pour la Suisse le 8 mai 19742 - RS 0.812.21 http://www.admin.ch/ch/f/rs/i8/0.812.21.fr.pdf  
Federal Council - Message regarding the law on therapeutic products - (108 pages) http://www.bag.admin.ch/heilmitt/gesetz/f/botsch02.pdf 
Outcome - home page -"support our clients in the pharmaceutical, biotechnology and medical device industries in the launch and commercialization of their products" http://www.outcomes.ch/index.htm 
RCC - home page - "provides comprehensive services for the assessment of health and environmental effects of" pharmaceutical products http://www.rcc.ch  
PhRMA - New Drug Approvals in 2001 - January 2002 - (18 pages) http://www.phrma.org/searchcures/newmeds/resources/2002-01-25.46.pdf 
FDA- International Conference on Harmonization - Public Meeting - Transcripts - 10:30 a.m.- Thursday, January 17, 2002 http://www.fda.gov/cder/audiences/iact/meeting_transcript_011702.htm 
John Goldsmith - The Exogenous Regulator: Explaining Variation in Time to Approve Generic Drugs - November 2000 - DRAFT Please do not cite or disseminate without permission - (62 pages) http://www.cramton.umd.edu/workshop/papers/goldsmith-the-exogenous-regulator.pdf 
Draft - Ordonnance sur les médicaments (ordonnance sur les médicaments, OMéd) http://www.bag.admin.ch/heilmitt/gesetz/verord/f/vam.pdf 
Rapport explicatif concernant l’ordonnance sur les médicaments OMéd - Project of September 2000 http://www.bag.admin.ch/heilmitt/gesetz/verord/f/vam_erl.pdf 
Draft - Ordonnance de l'ISPT sur les exigences relatives à l'autorisation de mise sur le marché des médicaments
(ordonnance sur les exigences relatives aux médicaments, OEMéd)
http://www.bag.admin.ch/heilmitt/gesetz/verord/f/amzv.pdf 
Draft - Ordonnance sur les autorisations dans le domaine des médicaments - OAMéd http://www.bag.admin.ch/heilmitt/gesetz/verord/f/ambv.pdf 
Rapport explicatif concernant l’ordonnance sur les autorisations dans le domaine des médicaments - OAMéd - Project of September 2000 http://www.bag.admin.ch/heilmitt/gesetz/verord/f/ambv_erl.pdf 
Draft - Ordonnance sur les dispositifs médicaux - Odim http://www.bag.admin.ch/heilmitt/gesetz/verord/f/mepv.pdf 
Rapport explicatif concernant l’ordonnance sur les dispositifs médicaux - Odim - Project of September 2000 http://www.bag.admin.ch/heilmitt/gesetz/verord/f/mepv_erl.pdf  
Draft - Modification de l’ordonnance sur les médicaments http://www.bag.admin.ch/heilmitt/gesetz/verord/f/ergaenzungamv.pdf 
Rapport explicatif concernant la modification de l’ordonnance sur les médicaments - OMéd - Project of December 2000 http://www.bag.admin.ch/heilmitt/gesetz/verord/f/ergaenzungamv_erl.pdf  
Draft - Ordonnance de l’Institut suisse des produits thérapeutiques sur l’autorisation simplifiée de médicaments http://www.bag.admin.ch/heilmitt/gesetz/verord/f/vvza.pdf 
Rapport explicatif concernant l’ordonnance de l’Institut suisse des produits thérapeutiques
sur l’autorisation simplifiée de médicaments - Project of December 2000
http://www.bag.admin.ch/heilmitt/gesetz/verord/f/vvza_erl.pdf 
Draft - Ordonnance de l’Institut suisse des produits thérapeutiques sur la mise sur le marché des médicaments homéopathiques et des médicaments anthroposophiques sans indications http://www.bag.admin.ch/heilmitt/gesetz/verord/f/vhom.pdf 
Rapport explicatif concernant l’ordonnance de l’Institut suisse des produits thérapeutiques
sur la mise sur le marché des médicaments homéopathiques et des médicaments
anthroposophiques sans indications - Project of December 2000
http://www.bag.admin.ch/heilmitt/gesetz/verord/f/vhom_erl.pdf 
Draft - Ordonnance sur les inspections dans le domaine des médicaments http://www.bag.admin.ch/heilmitt/gesetz/verord/f/vinsp.pdf 
Rapport explicatif concernant l’ordonnance sur les inspections dans le domaine des médicaments - Project of December 2000 http://www.bag.admin.ch/heilmitt/gesetz/verord/f/vinsp_erl.pdf 
Rapport explicatif concernant le projet de modification de - l’ordonnance du 29 mai 1996 sur les stupéfiants et les substances
psychotropes - Ostup - et de l' ordonnance sur les précurseurs - Opréc
http://www.bag.admin.ch/heilmitt/gesetz/verord/f/aendbetm_erl.pdf 
Draft -Ordonnance sur les stupéfiants et les substances psychotropes http://www.bag.admin.ch/heilmitt/gesetz/verord/f/aendbetm.pdf 
Draft - Ordonnance sur les précurseurs et autres produits chimiques utilisés pour la fabrication des stupéfiants et de substances psychotropes http://www.bag.admin.ch/heilmitt/gesetz/verord/f/aendvorlv.pdf 
FDA - Mifepristone Information (home page) http://www.fda.gov/cder/drug/infopage/mifepristone/ 
FDA, CDER, New and Generic Drug Approvals: 1998-2001 http://www.fda.gov/cder/approval/index.htm 
Pharmaceutical Inspection Convention and Pharmaceutical Inspection Cooperation Scheme http://www.picscheme.org/index.htm 
Several articles on the history of FDA - Food and Drug Law Journal 50th anniversary Special Issue - 1995 http://www.fdli.org/pubs/Journal%20Online/jour_toc/vol50_Special.html 
Sheila R. Shulman and Jeffrey S. Brown - The Food and Drug Administration’s Early Access and Fast-Track Approval Initiatives: How Have They Worked? - 50 Food and Drug Law Journal 385-388 (1995) - (29 pages)  http://www.fdli.org/pubs/Journal%20Online/50_4/art4.pdf 
Stephen H. McNamara - Dietary Supplements of Botanicals and Other Substances: A New Era of Regulation - 50 Food and Drug Law Journal341-348 (1995) - (8 pages) http://www.fdli.org/pubs/Journal%20Online/50_3/art1.pdf 
Linda R. Horton - Medical Device Regulation in the European Union - 50 Food and Drug Law Journal 461-476 (1995) - (16 pages) http://www.fdli.org/pubs/Journal%20Online/50_3/art11.pdf 
Elizabeth C. Price - Teaching the Elephant to Dance: Privatizing the FDA Review Process - 51 Food and Drug law Journal 651-676 (1996) - (26 pages) http://www.fdli.org/pubs/Journal%20Online/51_4/art12.pdf